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CanCURE

The Canadian HIV Cure Enterprise (CanCURE) is a research collaboratory focused on studying HIV persistence during antiretroviral therapy and developing strategies towards a sustainable HIV remission. Our innovative scientific program is supported by the Canadian Institutes of Health Research (CIHR).

CanCURE Photo Gallery

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Available Positions

Research Assistant or Associate

Available at the Research Institute of McGill University Health Centre (RI-MUHC) to work on CIHR-funded research studies on HIV immunology. The candidate will be supervised by Dr Cecilia Costiniuk, Associate Professor in Infectious Diseases at McGill.

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Postdoctoral Fellow 

Available at the Research Institute of McGill University Health Centre (RI-MUHC) to work on CIHR-funded research studies on HIV immunology. The candidate will be supervised by Dr Cecilia Costiniuk, Associate Professor in Infectious Diseases at McGill.

 

                          Postdoctoral Fellow

Human Immunodeficiency Virus (HIV)-host interactions governing HIV persistence in different models of humanized mice. Dr. Eric Cohen, Montreal Clinical Research Institute (IRCM, Montreal)

Publications

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Clain et al. Early ART reduces viral seeding and innate immunity in liver and lungs of SIV-infected macaques. JCI insight. July 2023

 

Gantner et al. HIV rapidly targets a diverse pool of CD4+ T cells to
establish productive and latent infections. Immunity. March 2023

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Colas et al. Generation of functional human T cell development in NOD/SCID/IL2rγnull humanized mice without using fetal tissue: Application as a model of HIV infection and persistence. Stem Cell Reports. February 2023

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Fert et al. Targeting Th17 cells in HIV-1 remission / cure interventions. Trends in Immunology. July 2022

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Tremblay et al. Bryostatin-1 Decreases HIV-1 Infection and Viral Production in
Human Primary Macrophages. Journal of Virology. February 2022

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Murooka et al. T cell migration potentiates HIV infection by
enhancing viral fusion and integration. Cell Reports. February 2022

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Salinas et al. Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth. PNAS. November 2021

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Planas et al. Peculiar Phenotypic and Cytotoxic Features of Pulmonary Mucosal CD8 T Cells in People Living with HIV Receiving Long-Term Antiretroviral Therapy. EBioMedicine. March 2021​​

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Routy et al. Beyond the Absence of CD4 T-Cell Count: A Novel Genetic CD4 T-Cell Deficiency Disorder With a Contingency Plan. J Infect Dis. February 2021

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Peng et al. Differences in HIV burden in the inflamed and non-inflamed colon from a person living with HIV and ulcerative colitis. J Virus Erad.​ February 2021

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Abdel-Mohsen et al. Recommendations for measuring HIV reservoir size in cure-directed clinical trials. Nature Med. September 2020 

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Gantner et al. Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART. Nature Communications. August 2020

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