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Lay Summaries of research

The Canadian Institutes of Health Research (CIHR) -and other grant distributing agencies- fund research involving human participants. In their guidelines, they incorporate directives to distribute research results so that benefits of knowledge creation spread across all interested parties. Reaching out to the public and communities affected by HIV is one of the most critical dissemination efforts.


Within CanCURE, we hope the posting of clear summaries of results from the team’s studies will increase trust in the research enterprise, promote collaboration and advocacy and encourage healthy discussion of issues to advance HIV Cure research. We will use this space on our website to post summaries when research involving human participants who volunteered either by providing biological samples and/or testing an intervention in a clinical trial led to a publication of those discoveries.

Information sheet for Busca et al., «cIAP1/2 -TRAF2-SHP-1-Src-MyD88 Complex Regulates Lipopolysaccharide-Induced IL-27 Production through NF-kB Activation in Human Macrophages» The Journal of Immunology, Mar 201

Information sheet for Rao et al. «The RNA surveillance proteins UPF1, UPF2 and SMG6 affect HIV-1 reactivation at a post-transcriptional level» Retrovirology, June 2018

Information sheet for Tietjen et al., «Inhibition of NF-κB-dependent HIV-1 replication by the marine natural product bengamide A» Antiviral Research ,  April 2018

Information sheet for Ranganath et al., «The oncolytic virus, MG1, targets and eliminates latently HIV-1-infected cells: implications for an HIV cure.» The journal of infectious diseases, Dec 2017

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