A recent paper discussing immune privilege – how the immune system protects the testes and other compartments of the body – featuring Jean-Pierre Routy was recently published in Nature Medicine. Author Shraddha Chakradhar explain what is immune privilege and how is compares in different compartment of the body (brain, testis, eyes). He also explains how this affects viral infection such as HIV. Dr. Routy, interviewed for the article, explains how partnering with a gender reassignments clinic to access precious tissues helped with the research. Moreover, research on this subject can be applied to cancer studies: learning form pathways implicated in immune privilege may help understand how tumors escape the immune system.
Illustration: Peter Cull/Science Source