New study looks at how the testes act as a potential sanctuary site for HIV
From left to right: Reina Bendayan, Jean-Pierre Routy and Nicolas Chomont
CanCURE Co-Investigator Dr. Reina Bendayan (University of Toronto) has published a study in collaboration with CanCURE Co-Investigators Dr. Jean-Pierre Routy (Research Institute of the McGill University Health Centre) and Dr. Nicolas Chomont (CHUM Research Centre) in the Journal of antimicrobial chemotherapy. Their work suggests that the testes represent a compartment of the human body which can restrict access of certain antiretroviral drugs used to treat HIV-infected individuals. Hence, the researchers contribute to better understanding how antiretroviral concentrations needed for efficient viral suppression are difficult to reach in this potential sanctuary site for HIV. Portions of this project were presented in 2015 at the annual Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle, as well as the 7th International Workshop on HIV Persistence during Therapy in Miami.