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CanCURE

The Canadian HIV Cure Enterprise (CanCURE) is a research collaboratory focused on studying HIV persistence during antiretroviral therapy and developing strategies towards a sustainable HIV remission. Our innovative scientific program is supported by the Canadian Institutes of Health Research (CIHR).

© IAS/photo: Steve Forrest

November 24, 2020

The sixth Annual Meeting of the Canadian HIV Cure Enterprise (CanCURE) was held virtually via Zoom and Slack on October 29th and 30th2020. This research consortium focused on HIV Cure is led by Dr. Éric A. Cohen, Research Professor at the IRCM and...

August 17, 2020

Clonal expansions occur in the persistent HIV reservoir as shown by the duplication of proviral integration sites. However, the source of the proliferation of HIV-infected cells remains unclear. Here, we analyze the TCR repertoire of single HIV-in...

July 23, 2020

During these times of uncertainty and growing change, CanCURE is continually committed and focused on studying HIV persistence during antiretroviral therapy and developing strategies towards a sustainable HIV remission. With monthly meetings joini...

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Available Positions

Postdoctoral Fellow

Human Immunodeficiency Virus (HIV)-host interactions governing HIV persistence in different models of humanized mice. Dr. Eric Cohen, Montreal Clinical Research Institute (IRCM, Montreal)

PhD trainee/Postdoc

Immunity during HIV infection, Dr. Cecilia Costiniuk and Mohammad-Ali Jenabian, IR-MUHC, Montreal (2 positions available)

Postdoctoral Fellow 

Immunity during HIV infection Dr. Cecilia Costiniuk, MUHC, McGill, Montreal

Publications

 Abdel-Mohsen et al. Recommendations for measuring HIV reservoir size in cure-directed clinical trials. Nature Med. September 2020 

Gantner et al. Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART. Nature Communications. August 2020

 

Zhang et al. Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With all-trans Retinoic Acid. Frontiers in Microbiology. May 2020

Rabezanahary et al. Despite early antiretroviral therapy effector memory and follicular helper CD4 T cells are major reservoirs in visceral lymphoid tissues of SIV-infected macaques. Mucosal Immunol. Nov 2019

©2019 CanCURE

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Purchased Photo - myeloid cells and CD4+